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Cryptosporidium spp. in wild and captive Australian flying foxes (genus: Pteropus)

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posted on 28.03.2022, 11:45 authored by Sabine E. Schiller
Spillover of zoonotic pathogens from wildlife to humans is a primary threat to global health, but the potential impacts of reverse pathogen transmission (zooanthroponosis) is still largely unexplored. Increasing establishment of wildlife species in regional and urban Australia potentially increases risk of human-borne pathogen spillover at the human/wildlife interface. To explore this issue, the occurrence of the protozoan parasite Cryptosporidium was investigated in urbanised flying fox populations. Cryptosporidium infects a wide range of vertebrates, with species varying in host specificity. In humans, C. hominis and C. parvum are responsible for the majority of infections. PCR screening of faecal samples (n = 281) from seven wild and two captive flying fox populations identified the presence of Cryptosporidium in 3.2% of samples, with a prevalence of 1.7% in wild versus 6.3% in captive individuals (χ² = 3.708, DF = 1, p= 0.054). Using multilocus sequencing (18s rRNA, actin and gp60) C. hominis was identified in captive animals (n = 2) and four novel Cryptosporidium genotypes in wild and captive animals (n = 7). This is the first study to report the presence of Cryptosporidium spp. in Australian flying foxes and findings indicate zooanthroponotic transmission of Cryptosporidium from humans to flying foxes.

History

Table of Contents

1. Introduction -- 2. Materials and methods -- 3. Results -- 4. Discussion -- 5. References -- 6. Appendix.

Notes

Includes bibliographical references

Awarding Institution

Macquarie University

Degree Type

Thesis MRes

Degree

MRes, Macquarie University, Faculty of Science and Engineering, Department of Biological Sciences

Department, Centre or School

Department of Biological Sciences

Year of Award

2016

Principal Supervisor

Michelle L. Power

Rights

Copyright Sabine E. Schiller 2015. Copyright disclaimer: http://mq.edu.au/library/copyright

Language

English

Extent

1 online resource (51 pages) illustrations, maps

Former Identifiers

mq:52307 http://hdl.handle.net/1959.14/1126901