Macquarie University
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Enhancement of verb retrieval ;: neuromodulation, repetition priming, and aphasia rehabilitation

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posted on 2022-03-28, 01:24 authored by Vânia De Aguiar
There is an increasing interest in enhancement of cognitive functions. Cognitive enhancement can play a role in improving performance in young individuals, in the maintenance of cognitive functions in aging, and in the rehabilitation of impaired cognitive functions in various neurological conditions, such as stroke. Furthermore, data from studies of cognitive enhancement can be used to increase our understanding of the architecture of the cognitive system, and of the interactions between the building blocks of cognition. This dissertation addresses the enhancement of verb retrieval. Verbs are central to the process of sentence construction, and play therefore a major role in communication. The process of verb retrieval is vulnerable to brain damage, being selectively disrupted in a high proportion of patients who present with aphasia after stroke. Nonetheless, there is relatively little research on the treatment of verb retrieval in aphasia in comparison to other types of impairment. This thesis has a specific focus on understanding the mechanisms of enhancement in verb retrieval, both in healthy individuals, and patients with aphasia. This enhancement is studied with behavioral techniques and transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique.


Table of Contents

Chapter1. General introduction -- Chapter 2. tDCS in post-stroke aphasia : the role of stimulation parameters, behavioral treatment and patient characteristics -- Chapter 3. ERP signatures of repetition priming in spoken word production and the absence of tDCS-related enhancement -- Chapter 4. Item specific improvement and generalization in verb retrieval : predictors and mechanisms of aphasia recovery -- Chapter 5. Can tDCS enhance item-specific effects and generalization after linguistically motivated aphasia therapy for verbs? -- Chapter 6. General discussion.


"A Doctoral thesis submitted in partial fulfillment of the requirements for the degree of Doctor in Philosophy at the International Doctorate for Experimental Approaches to Language and Brain (IDEALAB)" -- title page. Theoretical thesis. Bibliography: pages 174-219

Awarding Institution

Macquarie University

Degree Type

Thesis PhD


PhD, Macquarie University, Faculty of Human Sciences, Department of Cognitive Science

Department, Centre or School

Department of Cognitive Science

Year of Award


Principal Supervisor

Lyndsey Nickels

Additional Supervisor 1

Paul Sowman

Additional Supervisor 2

Gabriele Miceli


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1 online resource (xvi, 264 pages)

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