01whole.pdf (4.39 MB)
Download file

Face processing in typical and congenitally prosopagnosic adults: behavioural and neuroimaging investigations

Download (4.39 MB)
thesis
posted on 28.03.2022, 17:52 authored by Davide Rivolta
Faces are crucial for human social interaction. For most people, recognizing familiar faces is seemingly effortless. However, people who suffer from congenital prosopagnosia (CP) never develop this skill. The current thesis consists of a series of five studies investigating the cognitive as well as neural aspects of both atypical (CP) and typical face processing. In the first study, I adopted "covert" (implicit) face recognition tasks to characterize the exact nature of the cognitive impairment of a participant with CP, showing that "covert tasks" can represent a more sensitive assessment tool for this purpose than traditional "overt tasks". In the second study, I demonstrated that covert recognition is a general feature of CP by assessing a group of eleven CPs with three behavioural tasks. Importantly, I showed that different behavioural tasks vary in the sensitivity of detecting covert recognition. In a third study, by coupling Magnetoencephalography (MEG) with structural brain images (MRIs), I demonstrated that CPs show typical face-selective neuromagnetic activity within the right lateral occipital cortex (rLO) and fusiform gyrus (rFG). Crucially, I characterized the link between brain activity and behaviour, by examining the correlation between MEG activity and the performance on a series of face processing tasks. In a fourth study, using functional Magnetic Resonance Imaging (fMRI), I demonstrated that the pattern of fMRI activity within the right anterior temporal lobe (rAT) differs between CPs and people with normal face processing skills. Finally, in a fifth study, I investigated the spatio-temporal dynamics of typical face perception by coupling MEG recording with MRIs. I demonstrated that the human visual system can categorize places just as rapidly as it categorizes faces, suggesting that early categorization of visual stimuli may be a more general phenomenon than so far assumed. Altogether, these five studies make a significant contribution to our current understanding of the cognitive as well as neural mechanisms underlying face processing difficulties in CP. In addition, they provide crucial insights into the temporal dynamics of typical visual processing.

History

Table of Contents

1. General introduction and literature review -- 2. Semantic information can facilitate covert face recognition in congenital prosopagnosia -- 3. Covert face recognition in congenital prosopagnosia: a group study -- 4. The face-specificity of the M170 correlates with behavioural performance: insights from congenital prosopagnosia -- 5. Multi-voxel pattern analysis of fMRI data reveals abnormal anterior temporal lobe activity in congenital prosopagnosia -- 6. An early category-specific neural response for the perception of places -- 7. General discussion.

Notes

"This thesis is submitted in fulfillment of the requirements for the degree of Doctor of Philosophy (PhD) December 2010" Thesis by publication. Includes bibliographical references

Awarding Institution

Macquarie University

Degree Type

Thesis PhD

Degree

PhD, Macquarie University, Faculty of Human Sciences, Macquarie Centre for Cognitive Science (MACCS)

Department, Centre or School

Macquarie Centre for Cognitive Science

Year of Award

2011

Principal Supervisor

Max Coltheart

Rights

Copyright Davide Rivolta 2011. Copyright disclaimer: http://mq.edu.au/library/copyright

Language

English

Extent

1 online resource (x, 230 pages) illustrations

Former Identifiers

mq:71901 http://hdl.handle.net/1959.14/1279296