Longitudinal fibular deficiency: lower limb function and quality of life of children and young people

This thesis builds upon the small evidence-base for longitudinal fibular deficiency in children and young people, specifically in terms of lower limb function and quality of life. To date, research on individuals with longitudinal fibular deficiency has focused on impairments of body functions and structures with minimal investigation of activity limitations and participation restrictions. Studies suggest that affected adults have similar quality of life to published normative values, but little is known about quality of life and lower limb function of children and young people with this condition. Therefore, a cross-sectional study was undertaken exploring these outcomes in 17 affected children compared to 213 unaffected peers. Children and young people reported, on average, significantly reduced lower limb function and quality of life compared to unaffected peers. Knee function in younger children was significantly reduced, however, in young adults it was closer to normal. Ankle function was reduced in children and young people when compared to unaffected peers. Early and individualised clinical assessment of these outcomes appears to be warranted. Further research assessing the effectiveness of treatment interventions, longitudinal studies assessing individual changes over time, and qualitative investigations of a child's function and quality of life are recommended.