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The influence of the laboratory environment on the measurement of language lateralisation

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posted on 28.03.2022, 21:23 authored by Hannah Rapaport
Hemispheric lateralisation can be assessed with both functional magnetic resonance imaging (fMRI) and functional transcranial Doppler ultrasonography (fTCD). However, concordance between these techniques is imperfect. This discrepancy may be partially explained by differences in the fMRI and fTCD laboratory environments: while fMRI occurs in a noisy, confined space in which subjects lie supine, fTCD typically occurs in a quiet, unconfined space in which subjects sit upright. This study investigated the influence of the fMRI and fTCD laboratory environments on the measurement of language lateralisation. Across two experiments, fTCD was used to measure the consistency of language lateralisation while participants performed a word generation task either twice in an fTCD environment (control condition), or once in an fTCD environment and then in a simulated fMRI environment (experimental condition). Relative to the control condition, test-retest reliability of lateralisation estimates was considerably poorer in the experimental condition. Consistent with this, several participants in the experimental condition switched lateralisation categories between the two testing sessions. These findings suggest that the laboratory environment may partially account for the discordance between fMRI and fTCD lateralisation estimates. Future research should embrace protocols that aim to reduce the interference of the laboratory environment, such as noise-cancelling headphones and open, multi-postural fMRI, to further our understanding of hemispheric lateralisation.

History

Alternative Title

Influence of environment on lateralisation.

Table of Contents

Introduction --- Experiment 1 -- Experiment 2 -- General discussion -- Conclusion -- Appendices.

Notes

"ARC Centre for Excellence in Cognition and its Disorders, Department of Cognitive Science, Faculty of Human Sciences, Macquarie University" -- title page. Bibliography: pages 67-78 Running title: Influence of environment on lateralisation. Empirical thesis.

Awarding Institution

Macquarie University

Degree Type

Thesis MRes

Degree

MRes, Macquarie University, Faculty of Human Sciences, Department of Cognitive Science

Department, Centre or School

Department of Cognitive Science

Year of Award

2017

Principal Supervisor

Nicholas Badcock

Rights

Copyright Hannah Rapaport 2017. Copyright disclaimer: http://mq.edu.au/library/copyright

Language

English

Extent

1 online resource (99 pages) graphs, tables

Former Identifiers

mq:70570 http://hdl.handle.net/1959.14/1265576